Today I will share information from the #ASCO26 session Let's Debate: Surgery Versus NACT in Advanced Ovarian Cancer , May 31, 2026 with Dr Mahner- Surgery and Dr Olawaiye NACT and Dr Bixel distilling the information.
I posted this to X the day I viewed the session.
On Demand #ASCO26 Let's Debate: Surgery Versus NACT in Adv OC 5/31
— Dee Sparacio (@womenofteal) June 1, 2026
Dr Mahner- Surgery Dr Olawaiye NACT
I wish I was in the room for this debate! Dr Bixel did an excellent job highlighting patient qualities when making the decision whether to use Surg or NACT. #gyncsm pic.twitter.com/DnP5rr2T9Q
Let me share a few other slides from the debate.
Dr Mahner shared information about the TRUST and other trials and then looked at real world data regarding surgery and NACT to reach his conclusion that primary surgery is preferred when certain conditions exist.
Then Dr Olawaiye spoke about NACT - neoadjuvant chemotherapy in late stage ovarian cancer and reached this conclusion to support his position.
Dr Bixel distilled the data presented during the debate. She spoke of the use of different scoring methods to predict whether surgery was appropriate or not ( Peritoneal Cancer Index and Fagotti Score / Predictive Index Value) and then drew her conclusions.
(There is an article by Dr Bixel in the ASCO Education Book - https://ascopubs.org/doi/10.1200/EDBK-26-520652 - give a read for more details. )
The Key take away for me was:
Shared decision making is key! Patient Factors ( frailty, co-morbidities etc) and amount and location of disease must be discussed with patients. This way each patient is receiving the best treatment for their circumstances.
Dee
Every Day is a Blessing!
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