Follow tweets from the ASCO of course.
My Twitter news stream was filled with comments on these two non-gyn cancer studies.
Breast Cancer -
The Adjuvant Chemo and 21 Gene Expression Assay study reported at ASCO by Dr J Sparano may be found in this NJEM article https://www.nejm.org/doi/10.1056/NEJMoa1804710.
"Investigators “found that gene tests on tumor samples were able to identify women who could safely skip chemotherapy and take only a drug that blocks the hormone estrogen or stops the body from making it.” From the ASCO Cancer in the News e-mail .
Lung Cancer - Keytruda Study (Pembroluzimab)
Keytruda "boosts the immune system outperforms chemotherapy in fighting advanced lung cancer, a new trial shows. Keytruda (pembrolizumab) extended life four to eight months longer than chemotherapy in lung cancer patients whose immune systems had been duped by their cancer cells.
"This trial shows that pembrolizumab used alone improves survival as opposed to chemotherapy," said lead researcher Dr. Gilberto Lopes, a medical oncologist with the Sylvester Comprehensive Cancer Center at the University of Miami Health System." From HealthDay / ASCO Cancer in the News e-mail.
https://consumer.healthday.com/cancer-information-5/lung-cancer-news-100/cancer-drug-keytruda-a-new-weapon-against-advanced-lung-tumors-734492.html
Lopes: KN-042 ph3 of pembro alone v doublet chemo for 1st line squam or non-squam NSCLC w/PD-L1 1% or higher. OS signif better w/pembro, though HR for OS in PD-L1 1-49% no better w/pembro. Better tolerability w/pembro. Debate will be pembro + or - chemo for most. #ASCO18 #LCSM pic.twitter.com/UlatgRtpqc— H. Jack West, MD (@JackWestMD) June 3, 2018
Now on to the gyn Tweets/ Studies.
OVARIAN CANCER :
Keynote - niraparib and pembrolizumab
(Median duration response rate of 9.3 months)TOPACIO/Keynote results: niraparib and pembrolizumab in recurrent platinum resistant ovarian cancer #ASCO18 #GynCSM pic.twitter.com/Zeumhr8q98— Annie Ellis (@Stigetta) June 3, 2018
Vaccine Trial
Exciting early results from Dendritic cell vaccine trial in #ovariancancer #gyncsm #ASCO18 @Aurora_Cancer pic.twitter.com/UhhvSV4LeR— Elizabeth L. Dickson, MD, FACOG (@edicksonMD) June 3, 2018
— Elizabeth L. Dickson, MD, FACOG (@edicksonMD) June 3, 2018
Genetic Testing
@ShannonWestin Why we haven’t seen as many “home runs” in Gyn cancers—much more complexity and heterogeneity #gyncsm #ASCO18 pic.twitter.com/0ej005Iisa— Elizabeth L. Dickson, MD, FACOG (@edicksonMD) June 3, 2018
HPV / Cervical CancerDr. Elise Kohn on which patients should receive genetic testing #ASCO18 #GynCSM pic.twitter.com/wINaKGGeHA— Rivkin Center (@RivkinCenter) June 3, 2018
Could a single dose of an HPV vaccine confer enduring protection against #cervicalcancer, helping to address US & global health disparity? @NCIDrDoug thinks so & lrg RCT underway by @theNCI & @gatesfoundation to test hypothesis. #ASCO18 #gyncsm— Tatiana Prowell, MD (@tmprowell) June 3, 2018
Immune environment
Trial DesignMore and more need to understand the immune environment around tumor cells #ASCO18 #gyncsm pic.twitter.com/Vg3GDkDZtP— Elizabeth L. Dickson, MD, FACOG (@edicksonMD) June 3, 2018
Dr. Amit Oza lays out the opportunities for precision therapy and challenges that exist for trial design #ASCO18 pic.twitter.com/mXRwlNcOFK— Rivkin Center (@RivkinCenter) June 3, 2018
Communication
How well do patients and their oncologists agree on overall goals of #cancer care? Unfortunately, there's marked discordance about 33% of the time! Need to collectively raise our #communication skills as a field: https://t.co/FaxKSdtzSP #ASCO18 #pallonc #hpm @vitaltalk— Thomas LeBlanc, MD (@tomleblancMD) June 3, 2018
Cancer Prevention
Strong evidence to counsel patients to avoid alcohol, tanning beds, dietary fat and sedentary lifestyles. Excellent cancer prevention educational session! #ASCO18 @loconte pic.twitter.com/nsm9U1gFat— Jessica Hwang, MD (@viralreact) June 3, 2018
Will check into the #gyncsm and #ASCO18 tweet streams a few times today to catch more news from the meeting. If you are there feel free to use those hashtags or tag me @womenofteal in your posts.
Dee
Every Day is a Blessing!
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