Wednesday, February 22, 2012
Research: Freezing Tumors, Faulty Dendritic cells and Platelets
Check out some interesting research news.
Wayne State University researchers found freezing ovarian cancer tumors improved survival rates in women with late stage disease who present with a small number of tumors. Twenty-one women were in the study ("Cryoablation of Metastatic Ovarian Cancer for Local Tumor Control: Improved Survival and Estimated Cost-Effectiveness, ) using cryoablation.
OC Progression and Dendritic Cells
Using mouse models Wistar Cancer Center researchers have found that a women's own dendritic cells may aid in the progression of malignant ovarian cancer cells into metastatic disease. The dendritic cells alert the immune system to threats but also suppress other anti-tumor cells from working properly. Researchers are already working on reprogramming RNA to restore these dendritic cells to their tumor fighting role.
Journal Article- http://jem.rupress.org/content/early/2012/02/15/jem.20111413
News Article - http://www.news-medical.net/news/20120220/Targeting-patients-own-dendritic-cells-may-help-restore-the-immune-system.aspx
Thrombocytosis ( high platelet levels) and high levels of interleikin -6 was associated with advanced disease and shortened survival . The study analyzed 619 patients with epithelial ovarian cancerand then looked at human samples and mouse models to study the mechanism of the thromobcytosis.
Every Day is a Blessing!