Friday, January 27, 2012
A friend and fellow ovarian cancer survivor sent me a link to the article "Attacking "bad carbs" to fight ovarian cancer" which appeared in Beaker , the Sandford-Burnham Medical Research Institute's blog. . The article reports on glycobiology research by Michiko Fukuda, Ph.D. and her team.
Glycobiology is the study of glycoproteins. Glycoproteins are molecules made up of carbohydrates and proteins. The surface of epithelial cells are protected by carbohydrates. When a cell becomes cancerous the surface carbohydrates are altered and may contribute to cell growth and metastasis. Dr Fukuda and her postdocs worked with a monoclonal antibody (HMOCC-1) that attaches itself to the surface of malignant Ovarian Cancer cells. They developed a biochemical method to determine which modified carbohydrate the antibody attached itself to. The complete research article was published in the Journal of Biological Chemistry . Click here for a link to the article.
The more we understand the structure of ovarian cancer cells the better we can develop treatments.
Every Day is a Blessing!